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Nancy Guthrie search: FBI turns to Genealogy testing as leads grow cold

DeFi Daily News by DeFi Daily News
February 18, 2026
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The FBI says investigative genetic genealogy is now being used in the disappearance of Nancy Guthrie as authorities push forward with new forensic strategies. According to officials, DNA was recovered from a glove that matches the type worn by the individual captured on surveillance video outside Guthrie’s home the morning she vanished. However, when that DNA was entered into CODIS, there were no matches. Investigators also tested DNA collected from inside the home, but those results likewise failed to produce any hits in the national database. With traditional DNA comparisons coming up empty, the FBI is now turning to investigative genetic genealogy, a more advanced technique that uses publicly available genealogy databases to identify potential relatives of an unknown suspect. This method has been used in several high profile cases in recent years to generate new leads when conventional DNA searches did not deliver answers.
Authorities have not said how long the genetic genealogy process may take, but they remain hopeful it could provide a critical break in the case.

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