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Home Finance Business Finance

Wall Street’s Continued Uncertainty Over GLP-1s Impact

Anjalee Khemlani by Anjalee Khemlani
July 29, 2024
in Business Finance
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Wall Street’s Continued Uncertainty Over GLP-1s Impact
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Recent developments have cast a spotlight back onto the GLP-1 conversation, specifically how it affects stakeholders within the medical device industry. This renewed interest was triggered following Dexcom’s (DXCM) revelation that it had to lower its full-year financial forecast after not meeting earnings expectations last week. Dexcom, a leading provider of glucose monitoring devices, found itself at the center of Wall Street’s apprehensions concerning the GLP-1 drugs’ broader impact on related markets.

Nonetheless, it seems Dexcom’s predicament stands as an outlier rather than a precedent for the sector. Competitors such as Abbott (ABT) and Medtronic (MDT) have shown resilience, suggesting that Dexcom’s shortfall was not a direct consequence of the burgeoning interest in weight loss and diabetes medication. This situation has, at least momentarily, alleviated some of the anxiety circulating among investors about the disruptive potential of GLP-1 use on the medical device market.

Diving deeper into Dexcom’s announcement, the company pointed to an ineffective sales strategy as the root cause of its revised guidance. CEO Kevin Sayer shared during an earnings call, “It was a much more disruptive expansion that we’ve had in the past, and that did lead to a lot of disruption, particularly at the beginning of the quarter. We saw things getting better toward the end.” This acknowledgement pinpointed operational hurdles rather than market shifts influenced by GLP-1 therapies as the primary factor behind the disappointing earnings.

Not too long ago, food and beverage equities were also under scrutiny from Wall Street, with speculations that GLP-1-related weight loss trends could dim their long-term growth perspective. However, these forecasts have since been debunked. Meanwhile, predictions about the GLP-1 market itself are anything but modest, with analysts projecting its value to surge to $130 billion by 2030. This anticipation underscores the significant transformative potential GLP-1 therapies hold for the healthcare sector, though not without causing ripples across related industries.

The medical device arena, in particular, has experienced its fair share of volatility over the past months, intricately tied to developments surrounding GLP-1 information. A luminary moment occurred in June when Eli Lilly (LLY) disclosed that its GLP-1 formula, integral to the weight-loss drug Zepbound, showed efficacy in reducing episodes of sleep apnea, particularly among users of CPAP machines. Although this announcement initially seemed to cast a shadow over CPAP device manufacturers, including market frontrunner ResMed (RMD), CEO Mick Farrell adopted an optimistic stance. In an interview with Yahoo Finance, Farrell regarded the development as a “tailwind,” positing that increased awareness and diagnosis of sleep apnea fueled by such findings could, in fact, expand their customer base.

Furthermore, Farrell underscored the unintended boost in visibility and patient engagement that may arise from tech giants such as Apple (AAPL), Google (GOOG, GOOGL), Samsung, and the developers behind the Oura ring venturing into sleep monitoring technologies. This trend towards heightened awareness is anticipated to play a significant role in drawing more individuals into the dialogue about sleep apnea management, potentially broadening the market for CPAP devices.

Bay Saunders, 12, with Dexcom G6 patch on her arm for the treatment of her Type 1 diabetes, attends a Senate Appropriations Committee hearing on how the Special Diabetes Program is creating hope for those Living with Type 1 Diabetes, together with other children with Type 1 diabetes, Tuesday, July 11, 2023, in Washington. (AP Photo/Manuel Balce Ceneta) (ASSOCIATED PRESS)

Underpenetrated market

The narrative around GLP-1 has been somewhat overshadowed by dire predictions about various sectors based on initial data. However, industry experts are quick to point out that the real dynamics are much more nuanced, primarily moderated by supply side constraints. Analysts at JPM noted in an August 2023 insight, “Unless patients commit to using GLP-1s for life, which many aren’t keen to do, they’ll likely still progress to bariatric surgery, which remains extremely underpenetrated.”

This observation not only reflects on the bariatric surgery segment but also casts a broader light on other markets including continuous glucose monitoring systems and CPAP devices. In essence, the ‘underpenetrated’ marker signals ample room for growth and innovation, particularly as industry leaders embrace manufacturing expansions to meet GLP-1 demand.

Meanwhile, the competitive landscape for GLP-1 market share is heating up, with Eli Lilly and Novo Nordisk’s positions being challenged by ongoing clinical trials from pharmaceutical veterans like Roche (RHHBY), Amgen (AMGN), Pfizer (PFE), and biotech newcomer Viking Therapeutics (VKTX). Roche’s announcement of favorable early-stage trial results coupled with Viking stepping into final-stage clinical trials have notably agitated the market, impacting Eli Lilly’s stock with a steep decline. Such developments, however, have had a lesser impact on Novo’s market standing.

Anjalee Khemlani, Yahoo Finance’s senior health reporter, offers an encompassing view on the tale of GLP-1s, capturing the ebbs and flows from pharma’s advances to policy dynamics. For those keen on delving deeper into the financial intricacies and emerging narratives within the health sector, Khemlani’s insights on social media platforms are a resource not to be missed.

For those whose appetite for the latest in financial and business news remains unquenched, DeFi Daily News stands as a beacon of trending articles and in-depth analyses poised to shape the conversations driving markets and innovation.

In conclusion, while the journey of GLP-1s and their broader effect on the medical device industry has been tumultuous, it nestles within a larger story of technological advancement, market dynamics, and patient-centered healthcare evolution. As setbacks become stepping stones and challenges pave the way for innovation, the unfolding narrative promises a fascinating blend of science, business acuity, and healthcare progress. Embracing the complexity and navigating the winds of change, stakeholders across the spectrum can look forward to a future where disruptions are but milestones in the continuous quest for better health outcomes.



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